Prague Guide: 72 Hours in the City of a Hundred Spires

Discover how to make the most of a weekend in Prague with this 72-hour itinerary packed with history, charm, and must-see attractions.

f we could bottle the charm of a European city and label it “timeless,” Prague would be the top contender. Known as the “City of a Hundred Spires,” this Bohemian gem has enchanted visitors for centuries with its fairy-tale castles, cobblestone streets, and cultural vibrancy. Whether you’re a history buff, a foodie, or an art enthusiast, our Prague Guide will show you how to make the most of 72 hours in this magical city.

As Kafka once said, “Prague doesn’t let you go… this dear little mother has claws.”

Let’s dive into this Prague Guide and discover how to experience its iconic landmarks, indulge in its local flavors, and uncover its hidden gems.

Day 1: Unveiling the Historic Core

Day 1: Prague Guide to the Historic Core

Begin your journey with a walk to the Old Town Square (Staroměstské náměstí), the beating heart of Prague’s historic district. Arrive early to take in the grandeur of this medieval square, where you’ll find the Astronomical Clock, an intricate masterpiece that puts on a delightful show every hour.

Charles Bridge (Karlův most) comes next in your Prague Guide. This iconic bridge, lined with baroque statues, offers stunning views of the Vltava River. Pro tip: Stop at the stone plaque of St. John of Nepomuk to make a wish and ensure good luck on your Prague adventures.

Climb up to Prague Castle (Pražský hrad), the city’s crown jewel and the largest ancient castle complex in the world. Highlights here include St. Vitus Cathedral, the Old Royal Palace, and Golden Lane. Enjoy breathtaking views from the castle grounds as the sun sets over the city.

Don’t miss a visit to the Kafka Museum, where Prague’s most famous writer comes to life in surreal exhibits. Outside the museum, you’ll find a quirky fountain featuring two men “peeing” into the shape of the Czech Republic—classic Kafkaesque humor!

Wrap up your first day with a traditional Czech dinner featuring goulash or svíčková and a locally brewed beer. For dessert, treat yourself to Trdelník, a sweet pastry spiraled with sugar and cinnamon.

Day 2: Prague Guide to Culture, Art, and Modern Marvels

Start Day 2 with a visit to the Dancing House (Tančící dům). Often called “Fred and Ginger,” this modern architectural gem stands out against Prague’s historic skyline. Snap photos of its flowing curves and enjoy rooftop views if time permits.

Head over to the Jewish Quarter (Josefov) to explore a wealth of history. Visit the Old-New Synagogue and the Old Jewish Cemetery, where centuries of history are etched into each stone.

In Wenceslas Square, a vibrant hub of history and culture, grab a coffee and pastry to fuel up for the rest of your day. For an artistic experience, head to the National Gallery or the avant-garde DOX Centre for Contemporary Art.

Keep an eye out for the Hanging Statue of Sigmund Freud, a thought-provoking piece of public art by David Černý, symbolizing the struggles of the modern intellectual.

Cap off your day with a Czech dinner of roasted pork with dumplings or fried cheese, accompanied by a crisp pilsner beer.

Day 3: Prague Guide to Hidden Gems and Farewell Views

Spend your final morning in Vyšehrad, a historic fort overlooking the Vltava River. Stroll through its peaceful grounds and visit the Vyšehrad Cemetery, the resting place of Czech cultural icons.

Next, wander through Kampa Island, a tranquil spot with whimsical art installations like the crawling baby sculptures by David Černý.

For lunch, indulge in local classics such as beef tartare or potato pancakes, followed by the city’s signature apple strudel.

End your Prague Guide with a trip to Petrín Hill via the Petrín Funicular. The observation tower here, often called Prague’s Eiffel Tower, offers one last stunning view of the city. Before heading back, laugh your way through the Mirror Maze for a playful send-off.

Our Prague Guide proves that three days in the “City of a Hundred Spires” is enough to create lasting memories. From the Gothic spires to the cobblestone streets, Prague weaves a spell that stays with you long after you’ve left.